Transpose an Assay (Data Frame)

Transpose an object of class data.frame that contains assay measurements while preserving row (feature) and column (sample) names.

TransposeAssay(
  assay_df,
  omeNames = c("firstCol", "rowNames"),
  stringsAsFactors = FALSE
)

Arguments

assay_df	A data frame with numeric values to transpose
omeNames	Are the data feature names in the first column or in the row names of df? Defaults to the first column. If the feature names are in the row names, this function assumes that these names are accesible by the rownames function called on df.
stringsAsFactors	Should columns containing string information be coerced to factors? Defaults to FALSE.

Value

The transposition of df, with row and column names preserved and reversed.

Details

This function is designed to transpose "tall" assay data frames (where genes or proteins are the rows and patient or tumour samples are the columns). This function also transposes the row (feature) names to column names and the column (sample) names to row names. Notice that all rows and columns (other than the feature name column, as applicable) are numeric.

Recall that data frames require that all elements of a single column to have the same class. Therefore, sample IDs of a "tall" data frame must be stored as the column names rather than in the first row.

Examples

   x_mat <- matrix(rnorm(5000), ncol = 20, nrow = 250)
   rownames(x_mat) <- paste0("gene_", 1:250)
   colnames(x_mat) <- paste0("sample_", 1:20)
   x_df <- as.data.frame(x_mat, row.names = rownames(x_mat))

   TransposeAssay(x_df, omeNames = "rowNames")
#>                gene_1     gene_2      gene_3       gene_4      gene_5
#> sample_1  -1.40004352  0.2553171 -2.43726361 -0.005571287  0.62155272
#> sample_2  -0.83021426 -0.5035929 -1.19364118 -0.751723323  1.45584140
#> sample_3  -0.71152414  0.6621788  0.29113022  0.197958000 -1.20356611
#> sample_4   0.06391875 -0.9193322  0.90133529 -0.797728297  0.66822120
#> sample_5  -0.33671496 -0.2158402  0.62113229 -1.284026517 -1.30009244
#> sample_6   1.98351232 -1.8513784 -0.90978818 -1.951440016 -0.80027646
#> sample_7  -0.57852490 -0.1691090 -1.91923252 -1.534266387 -1.11476122
#> sample_8  -0.07134503  2.0957344  1.32208261  1.200558995 -0.78187457
#> sample_9  -0.16624618  0.1202185 -0.66173431 -0.530622574 -0.30141870
#> sample_10  2.28139492 -1.0422853  0.71230719  1.220747981  0.33601868
#> sample_11  0.38599496 -0.8388426 -0.53002759 -2.293182084  1.85526364
#> sample_12  0.53220725 -1.2969308 -0.11645988 -1.791435814  1.03763845
#> sample_13  1.12061565  0.3998977 -0.98452766 -0.502562184  0.98714844
#> sample_14 -0.17999302  0.9768564 -0.18660273 -0.034098393  1.48873220
#> sample_15 -2.90422064  0.3370126  0.76451066 -0.669378190 -0.16096887
#> sample_16 -0.02313530  0.2041608  0.04422852  0.627097488 -0.94724955
#> sample_17 -0.77331347  3.4805397 -0.61742197  0.520782443  0.59254025
#> sample_18  0.55419600  0.5607759 -1.43078881  0.256530937  0.44751298
#> sample_19  0.68571475 -1.5741902 -1.03920264  1.062892692 -1.27938089
#> sample_20 -0.56675822  0.5739729  0.91685224  1.182521119  0.08992096
#>                gene_6      gene_7     gene_8      gene_9      gene_10
#> sample_1   1.14841161 -1.82181766 -0.2473253 -0.24419961 -0.282705449
#> sample_2  -0.82860353  0.28977446 -0.4800535 -0.60482935  1.460110180
#> sample_3  -0.03981704  0.68698246  0.7052670  0.99144168  1.144248971
#> sample_4   0.15521430  0.12868809 -1.5330655  0.20236067 -0.717538653
#> sample_5  -0.37676946  0.10374865 -0.7035623  1.49741394 -0.302826878
#> sample_6  -1.86936160 -0.75057148 -0.5909384 -0.74209927  0.693512077
#> sample_7   1.59781164 -0.63980508  1.5666906 -1.44915571 -0.791503959
#> sample_8  -0.44147645 -0.24602813  0.3657922 -0.03413288  0.296227003
#> sample_9  -0.60230161 -0.31820808  0.3081960  0.79865009  1.750574467
#> sample_10 -0.27914794  0.07642213 -0.3545090  1.43265855  0.002671474
#> sample_11 -0.62471496  0.17587258 -1.3657889 -1.34551847  0.947265271
#> sample_12 -0.75173731  1.44332021  0.7341891 -1.05455799  0.030424727
#> sample_13  2.19148101 -0.16504221 -0.6860408  0.94139941 -0.164042843
#> sample_14 -0.18983930 -1.08930962  0.3710895 -1.02777011  0.014915848
#> sample_15  1.50726103 -0.12169384 -0.2434148  0.70815719 -0.480039667
#> sample_16 -1.12282694 -0.02032365  1.2250255  0.08305898 -1.885915170
#> sample_17 -0.90034685  1.47428132  1.0851326 -1.70668744 -1.168696300
#> sample_18  0.90915455 -0.65761179  0.2547813 -1.36295942 -1.151658044
#> sample_19 -1.76525996 -2.39468494  0.6618514  0.27920214 -1.975798133
#> sample_20 -1.42392593  0.18584016  0.6473436  0.12338155 -0.557040623
#>               gene_11     gene_12     gene_13     gene_14     gene_15
#> sample_1  -0.55369938  0.62898204  2.06502490 -1.63098940  0.51242695
#> sample_2   0.14967935 -1.43332110 -0.01030332 -0.21223603 -0.90634018
#> sample_3  -1.23891024  2.65489833 -0.15691719 -0.42349012 -0.19838706
#> sample_4   0.36169476  1.39900429  0.37269896 -1.56564429 -0.05169454
#> sample_5  -1.37683133  0.88317017  0.67142028  1.23002238  1.64546788
#> sample_6  -0.05946397 -1.86389510 -1.27450892 -1.78177081 -0.50859339
#> sample_7  -0.50448073  0.40182670  0.97139647 -0.57966302  1.60417979
#> sample_8  -0.22105977  0.18770616 -0.43806217 -0.08873358  0.63425003
#> sample_9   0.26533026  0.31715464 -0.14873638  0.32221895 -0.32420913
#> sample_10  0.34401251 -0.83032338  0.48211559 -0.68866037 -1.09335972
#> sample_11 -0.11573967 -0.42940449  0.07963198  1.00646399  1.75451875
#> sample_12 -0.62059166 -0.19350202  0.39360687 -0.03322616 -0.52872257
#> sample_13 -1.30233941 -0.72348400  1.39008874  0.68184063  0.46826028
#> sample_14 -0.52029856 -0.05224443 -1.43507957 -0.32797907 -1.28534762
#> sample_15 -0.31655127  0.51047124 -0.26626435  0.63643210 -1.01395559
#> sample_16  1.05692713  0.61291219  0.58965009 -0.06645134 -0.60810788
#> sample_17 -1.41945333  0.64597095 -0.42713279  1.18982815 -0.13985914
#> sample_18  0.09235619 -0.52610904 -0.94128250 -1.16038512  1.46321679
#> sample_19  0.49650693  1.35303163  0.65534828  0.20874837  0.47930452
#> sample_20 -0.42440379  1.42145636 -0.81089749 -0.67853461  1.87299949
#>              gene_16     gene_17     gene_18     gene_19     gene_20
#> sample_1  -1.8630115 -0.52201251 -0.05260191  0.54299634 -0.91407483
#> sample_2  -2.1021525  1.89336046 -0.96812584 -0.10260304  0.23995957
#> sample_3  -0.8948024  0.90426912  0.07964921 -1.25882722  1.02568511
#> sample_4   0.5140821  0.54989952  0.86781691  0.68436008 -0.16267998
#> sample_5  -0.1829260 -1.37925781  1.25060060 -1.87623677 -0.36878757
#> sample_6  -1.7368783  0.04048130 -0.12417946 -0.61275343  0.16066248
#> sample_7   0.2259733 -0.51485712 -0.82378824  0.33441525 -0.09349076
#> sample_8   0.8655382 -0.43059309  0.01303089  0.05124963  0.53863815
#> sample_9  -0.7833593 -0.01808712 -0.16919874 -0.16474300  0.71362242
#> sample_10  0.8410610  1.45413624  0.13724027  0.32554493  1.22372802
#> sample_11 -0.1193613  1.64399863 -1.31099776  0.36270142  1.36966549
#> sample_12  3.0710071 -1.42472377  0.33070126 -1.75947902 -1.01638420
#> sample_13  0.4209211 -0.80033126 -0.48845751  0.53900452  1.43517102
#> sample_14 -0.4255372  0.25747566  0.20131940  0.48207740  0.50663659
#> sample_15  0.9322307 -0.65078833  0.43617818 -0.16408940  1.26865639
#> sample_16  0.9473046  0.39316996 -0.38520593 -0.60926312 -0.38438515
#> sample_17  0.1893960  0.05758441 -0.58724613 -0.24141458  0.76380039
#> sample_18 -1.2270357  1.28912231  0.52198341  0.03864691  0.00548090
#> sample_19  1.1197219  0.35897006  1.19858349  0.56301946  0.36036431
#> sample_20 -0.9157497 -0.01212800 -1.11723798  0.26996560  1.51165399
#>               gene_21     gene_22     gene_23    gene_24      gene_25
#> sample_1   0.46815442  0.36295126 -1.30454355  0.7377763  1.888504929
#> sample_2   0.06089889 -2.17757603 -0.11786014  0.1122948  0.007886198
#> sample_3  -0.73077860 -0.19014551  0.52886469  0.5502105  0.549684337
#> sample_4  -1.78436472 -1.03714557  0.83014772  0.6073469 -0.122186361
#> sample_5  -2.12929731  0.33764603 -1.57457485 -0.1963194  0.915060108
#> sample_6  -0.66235963 -0.33485166  0.62301159  1.0281943 -1.134578240
#> sample_7   0.30406208 -0.47650753 -0.24131172  0.8241558 -1.555643970
#> sample_8   0.51967261 -2.42291128 -0.80629025 -0.4846800 -0.653077284
#> sample_9   0.23720904 -2.32268642  0.07904427 -0.4288064 -0.372714386
#> sample_10 -1.05331414  1.84033264 -2.23148428 -0.5958447 -0.230472754
#> sample_11 -0.34851240 -0.54547065 -0.02051968 -0.3388499  0.185592100
#> sample_12  1.03686204  0.03471228 -1.69369136 -0.3740821 -1.258362453
#> sample_13 -0.26183872 -1.41862372 -0.51379272  0.7723012  1.403682339
#> sample_14 -0.52669136 -0.56477398  0.04039804 -0.2007814 -0.904217194
#> sample_15  0.41543250 -0.04810428  0.19829295 -0.3886873 -0.452232286
#> sample_16 -0.90142367  0.87294589  0.56182126 -1.7572785 -0.812116095
#> sample_17 -0.67809673  0.83699414  0.04193947  0.9793096  1.496095654
#> sample_18  2.05096271  0.58400349 -0.71964038  0.3172920  0.166715654
#> sample_19  0.82536399 -0.04039258 -0.60545674 -0.4786488 -1.627036866
#> sample_20 -0.59315568 -1.61495437 -1.37389655  1.1927375  0.116453951
#>               gene_26     gene_27     gene_28      gene_29      gene_30
#> sample_1  -0.09744510 -0.93584735 -0.01595031 -0.826788954 -1.512399651
#> sample_2   1.87774387  2.15875655  0.70971452  0.766983379 -0.308211421
#> sample_3  -0.65954237  0.05742171 -2.80801051 -0.912259753 -0.782379163
#> sample_4   0.93312514 -0.96127668  0.25508171 -0.545401573  0.930360736
#> sample_5   1.07863654  1.45280285 -1.65328109 -2.761867518  0.264369164
#> sample_6   0.91691105  1.21387479 -0.68593246 -1.094568193  0.364874099
#> sample_7   0.09350128 -0.36694942 -0.12940880  0.407795520 -0.583968954
#> sample_8  -0.29376425 -0.27698900  0.13646959  1.067207722  0.001828103
#> sample_9  -0.04491861  1.40134303 -0.30087211 -0.965754406  1.683218482
#> sample_10  1.75631526  0.47570557  0.78264437 -1.146245649  0.950180682
#> sample_11  0.34586266 -0.79333237 -0.74863161 -1.846666644 -1.556824415
#> sample_12 -0.60810563 -1.36870786 -0.94216345  0.739857730  0.022094341
#> sample_13 -0.01580491 -1.02328956 -2.11639216  0.150371437 -0.520871198
#> sample_14  0.16665552 -0.52428478  0.01756390  0.948517187  0.270265784
#> sample_15 -0.13942143 -1.32519766  0.75406952  1.357852830 -1.220784861
#> sample_16  0.23869059  2.50600172 -0.98058716  1.566125055 -0.758867435
#> sample_17  1.38116716  0.17718685 -0.60455889 -0.006412554 -1.030917604
#> sample_18  2.50267853  0.40040871  1.07211199  0.055000963 -0.061363860
#> sample_19  1.09597335 -1.13061577  0.74940760  0.507040903  0.149227768
#> sample_20  0.19714199 -1.53435721  0.02661874  0.362927093 -0.677324332
#>                gene_31    gene_32     gene_33     gene_34      gene_35
#> sample_1   0.935363190  0.1764886  0.24368546  1.62354888  0.112038083
#> sample_2   1.012001849 -0.9190516  0.56338008  0.32248275  0.366674363
#> sample_3  -0.664104924  0.6263098 -0.50724821  0.27036133  0.467476865
#> sample_4  -0.537650558 -0.4524261 -0.43929097 -0.61622311  0.441634552
#> sample_5   1.024571594 -0.6591855 -0.38630438 -0.24249895  0.220593240
#> sample_6  -1.008017083  0.5549964  0.43606592  0.10537330 -0.253737853
#> sample_7  -0.193449890 -0.2695467  0.07365823  0.35723614  0.550428418
#> sample_8   0.140092252 -0.5205985  2.36581164 -1.69647441  0.682585584
#> sample_9  -0.776550575  0.2473014 -0.96714696 -1.03785442 -1.053599982
#> sample_10 -0.345227990 -2.4735515  1.37626416  2.47714507 -1.337234198
#> sample_11  0.002354941  1.4702063 -0.77748449  0.70461343  0.696606398
#> sample_12  0.548882732 -1.3506981 -0.64446763  1.04784473 -0.321393364
#> sample_13 -0.905454844 -0.7499869 -0.78657602 -0.55968187 -1.390851305
#> sample_14 -0.160941404  1.9651995  0.39554804  0.87371937  0.472324156
#> sample_15 -0.567918662 -1.1888496 -1.01227589 -0.43253149  0.345706392
#> sample_16  0.493845104 -0.3271505 -0.43487904  1.51972311  0.003677803
#> sample_17 -0.596619301  1.2300053 -2.12526394  0.54654128  1.011455341
#> sample_18 -1.076443591  0.5043043  0.53622455 -1.35497729  0.227506307
#> sample_19  0.756914894 -0.4272245 -1.34783112  0.08259559  1.153728116
#> sample_20 -0.386793166 -0.2107741 -0.63365248  0.07956932  0.238637053
#>               gene_36    gene_37    gene_38     gene_39     gene_40     gene_41
#> sample_1  -0.13399701 -1.9100875 -0.2792372 -0.31344598  1.06730788  0.07003485
#> sample_2   1.12983515 -0.9414981  0.2178376  1.41541229 -0.38373305 -0.17408637
#> sample_3   0.72399496  0.6138369 -0.6178692  0.22072490  1.12792660  1.81345434
#> sample_4   0.48259745  0.5421444 -2.2907847  0.31035185  1.40407898  1.37711764
#> sample_5  -1.48109003  0.7246912 -2.3775147 -0.06540921 -0.46970481 -0.28051629
#> sample_6  -0.97649123  0.3942178  1.0149030  0.63144381 -0.48339825 -1.52633394
#> sample_7   0.03840179 -1.6095753 -1.0497101  2.05203397  0.17643641  1.12830736
#> sample_8   1.36156198  1.9059558 -0.6728385 -1.06291143  1.63368316  0.54083036
#> sample_9  -0.20550744  1.3082666  0.5137219 -1.38535523 -1.00123881  0.30132568
#> sample_10  2.02415520  0.8595932  0.7284713  1.70297114 -1.34967197  0.08596097
#> sample_11  0.93197293  2.6161787 -1.4774923  0.07467723 -0.64077017  0.11492547
#> sample_12  0.03432588  1.0639484 -1.5876082 -1.58346240  0.11053133  0.24629884
#> sample_13 -0.28263060 -0.4802850 -0.9676210  1.77794098 -0.06908904 -0.42618825
#> sample_14 -1.48522645 -0.8361623 -0.6462692 -0.04743704  0.16775999 -0.09973867
#> sample_15  0.19092760  1.2874886 -0.2135043  0.59356130 -1.81579987 -0.46052457
#> sample_16 -0.40233995 -1.4954664 -0.9459855  0.90642951 -1.81386762 -0.95177543
#> sample_17  1.36717460  0.7078380 -0.1225159 -0.79940913 -0.17936000  0.10945286
#> sample_18 -2.52941871 -0.8185311 -1.5895300 -1.08249332  0.20580436 -1.08118232
#> sample_19  2.58684190 -1.6413688  0.1855768  0.80813951  0.46274190 -0.14086295
#> sample_20 -0.51154641 -0.8206424 -1.4975464 -0.15230202  1.31866600 -0.77596187
#>               gene_42    gene_43     gene_44    gene_45      gene_46
#> sample_1  -0.63912332 -0.0499649 -0.25148344  0.4447971  2.755417575
#> sample_2  -0.22174452 -1.0095287  0.48072527  1.6044073 -1.515024529
#> sample_3  -0.08382568  1.3677067 -0.62743462 -0.2166291 -0.683713824
#> sample_4   1.06039565  0.6321729  1.08492804  1.3564594  0.362424040
#> sample_5   0.57483659 -0.2056768  0.23488051  0.1106283  0.274202233
#> sample_6   0.61684228  1.2292868  0.15745303  1.4063421  0.396800917
#> sample_7   0.43500174  0.5488335  0.64741830  0.8784635  0.350797869
#> sample_8   1.45685797 -1.9337842 -0.88040080 -0.7977302 -0.886130974
#> sample_9   0.43768205 -0.6502751 -2.41967894  0.2755461 -0.217346388
#> sample_10  0.20420709 -0.9790504  0.59465080  1.0393171 -1.278834279
#> sample_11  0.74702130 -1.1184793  0.34100482  0.1250312  0.311369721
#> sample_12  0.05714992 -1.0833035  0.21630111 -0.8236855 -1.500780397
#> sample_13 -2.25140373 -0.9141710 -0.80052458 -0.7533059  0.660649173
#> sample_14  0.08599646 -0.3725740  0.18133254 -0.9068064  0.591157152
#> sample_15  0.74633798  0.8989959 -1.15546216 -0.2824238 -0.003256871
#> sample_16  1.12685210  0.1398891  0.10033998 -1.2045286 -0.083458296
#> sample_17  0.23092655 -1.2696632  0.62052581 -0.6423485  0.662357814
#> sample_18 -0.18879255  0.3127565  0.07471700 -0.6043449  0.045246650
#> sample_19 -1.83016730  0.4040879 -0.01375067 -0.1022412  0.202454445
#> sample_20  1.14813483  1.1409608 -0.33490119  0.6296591  0.734016764
#>               gene_47     gene_48     gene_49     gene_50      gene_51
#> sample_1   0.04653138  0.57770907  0.11819487 -1.91172049  0.862086482
#> sample_2  -1.41602391  0.87677733  0.62413241  2.11227729 -0.356124416
#> sample_3  -0.44470273  0.60648981  0.62418307 -0.69543107 -0.783639078
#> sample_4   2.16934446  0.13913051  1.37632653 -0.49144999  1.534915763
#> sample_5   1.57491963  0.56776783 -0.05961225 -0.14958771  0.266168788
#> sample_6   0.32642296 -1.45934331 -0.79929553  0.47001280 -1.150180520
#> sample_7   0.04987972  0.83574945 -0.28172520 -0.79167946  0.001653727
#> sample_8  -0.29482779 -0.88665169  0.09908467  0.72054690  1.000469215
#> sample_9   0.42081028  0.51449255 -0.97612025  0.82132277  1.487457423
#> sample_10 -0.31997882 -1.87282861  0.09132266  0.71236377 -0.110119494
#> sample_11  0.42644380 -1.26957932  0.86981105 -0.02357463  0.646068260
#> sample_12  1.22656701 -0.21586746  1.73378476 -1.43253568 -0.176478952
#> sample_13  1.72769564  0.78267858 -0.78181841 -0.12579755  1.015236070
#> sample_14  0.79251323  0.07687238 -0.06783720  0.43328805  0.049095403
#> sample_15  1.51502828  0.30938027 -0.46095882  0.29344757  0.070972006
#> sample_16 -0.79708225  1.10152458  0.10841041 -1.19050680  0.279921276
#> sample_17  0.24588428 -0.84789369 -0.43476741  0.88317595  0.586318680
#> sample_18  1.64853964 -0.75568298 -0.28817935 -0.73015051  0.524148520
#> sample_19  0.80332055 -0.58779325  2.11095854  0.10631918  0.288638282
#> sample_20  1.80204962 -1.14848006  1.21638135 -0.67346552 -1.151931160
#>               gene_52     gene_53     gene_54     gene_55       gene_56
#> sample_1  -0.24323674 -0.20608719  0.01917759  0.02956075  0.5498275418
#> sample_2  -1.06446421  1.07711654  1.18157557  0.19839209 -0.4004052494
#> sample_3  -0.95312386  1.79275607  0.34897670  0.25910377 -0.8059518969
#> sample_4  -0.41619872 -0.52054380  0.85058387  0.33449657 -0.8293517745
#> sample_5   0.52840324 -0.57938809  0.94219937 -0.70636136 -1.2754021003
#> sample_6  -0.27159672  0.45742422 -0.01695794 -0.54159436  0.8758134175
#> sample_7  -1.18753013  0.36241747 -0.54943532  0.69294984 -0.0608439164
#> sample_8   0.52799951  1.16360593  0.17313701  0.57791725 -0.1160087067
#> sample_9   0.52952179  1.88518177  0.72341993 -0.11530574  0.7813496652
#> sample_10 -1.05157582 -0.89140134 -0.61913804  0.25519905 -0.4393159166
#> sample_11  1.23267300 -1.28041054 -0.17608617  1.14891232  0.1064094245
#> sample_12  0.75631487 -0.98000771 -0.38642438  0.38151625  1.3457685390
#> sample_13  0.29467627 -0.29645879 -0.82228982  1.69154608 -1.4765457055
#> sample_14 -0.03280005 -0.51092478  0.35643054  0.41794614  0.5792052606
#> sample_15 -2.31375937  0.19270603 -0.35244145 -1.53329279 -1.7340692089
#> sample_16  0.77740777 -0.22108972 -0.13767684  0.11523004  1.5332695729
#> sample_17 -0.25669204  1.22013570  2.32588797 -1.30704234  0.0002714681
#> sample_18 -0.59170053 -1.18391199  1.20035313 -0.90807133 -1.5488176869
#> sample_19 -0.82812902  0.25924619 -0.49523074 -0.28950167  0.6406839533
#> sample_20 -0.87461434 -0.05600546 -0.64812078  0.26751883  0.3497561939
#>              gene_57     gene_58    gene_59     gene_60      gene_61
#> sample_1  -2.2741149  2.68255718 -0.3612213  0.21335575  1.074345882
#> sample_2   0.6161543  1.97415675  1.8846623 -1.58862055 -0.539923164
#> sample_3   0.1056647 -0.33359968  1.6418480 -0.64390586  0.587020562
#> sample_4  -0.2186959 -1.54508372  0.2332298  0.03106964  0.357865645
#> sample_5   0.7332599 -0.42020709 -0.2553751 -0.36923822  1.212448330
#> sample_6   0.7408382 -0.16481239 -0.7509643 -1.25336629 -1.036236261
#> sample_7  -1.1935409 -0.11990806 -0.7081080 -1.61666397  0.495847824
#> sample_8   0.9045211 -0.01658671 -0.9222974 -1.06011455 -1.787199640
#> sample_9   1.8029372 -0.38668922  2.7155402  1.24977062 -1.956745628
#> sample_10  1.4681492  0.83250613 -0.9137874 -0.27259543  0.751086555
#> sample_11  1.0525994  0.06350867  0.7602887 -0.58339123 -0.833176971
#> sample_12  0.9837487  0.08663730  0.4696699 -0.89290017  0.002229617
#> sample_13  0.9296936 -0.61383209  0.6175981 -0.83061518 -1.133375927
#> sample_14 -1.4751587  1.32380523  1.0306215  0.31737389 -1.111903788
#> sample_15  0.1418927 -0.21959960  0.5915645  0.24024791 -0.372564160
#> sample_16 -0.6557745  0.85837870 -1.1876706  0.53954038 -0.266362163
#> sample_17  1.1425116 -0.22194014 -0.2083146  0.74992271  0.117605618
#> sample_18  0.4080450  0.87234282 -1.8604777  0.20611760 -1.065526001
#> sample_19 -0.1414629 -0.87984739 -0.5236396 -0.61343660  0.749492399
#> sample_20 -1.2173020  0.08192791 -0.7956434 -0.58473794  0.534806561
#>               gene_62    gene_63    gene_64     gene_65     gene_66     gene_67
#> sample_1  -0.66508825  1.1139524 -0.2458964 -1.17756331 -0.97585062  1.06505732
#> sample_2  -1.16946146  0.5591060 -1.8193472  0.39334397  0.04213411  1.17966418
#> sample_3  -0.15040309 -1.7108218  1.4310326 -2.64521227 -1.03245741 -0.70746643
#> sample_4   1.60862422  1.4298543 -0.9483396  1.01570554  0.03773461 -1.74423940
#> sample_5  -0.44536301  1.1386675  0.1905235 -1.36639361 -1.29810260 -2.13709831
#> sample_6  -0.02943857 -0.2749438  0.4854515  0.91698203 -0.98534392 -1.49118975
#> sample_7   1.29975097 -1.6159855 -1.2503679  1.58213231  1.25252912 -0.20939570
#> sample_8  -1.06655178 -1.1298292  0.3872678  1.27026338 -1.64611783 -0.12360407
#> sample_9   0.66675609 -0.5369323  1.1217869  1.39415872  0.11220949  0.26312335
#> sample_10 -0.07685626  0.1471015 -0.3212382 -1.70314007 -0.76103844 -0.75902539
#> sample_11 -0.95527926  0.4681975  1.4893616  0.84563780 -0.09033036 -0.76097409
#> sample_12  0.15074768 -0.5745546  0.2351604  1.26585841 -1.39029804  0.11579572
#> sample_13 -0.15637832 -0.2430917 -1.1292644 -0.06219248  0.48708263 -0.05463695
#> sample_14  0.62121117  1.8091086  1.1139860  0.46535053 -1.06862973  0.25594028
#> sample_15  0.26454587  0.6515445 -0.4183198 -2.07876063  0.59095504 -0.70564074
#> sample_16  0.75817223 -1.0314020  1.0249315 -0.14526159  0.10922383 -1.47859879
#> sample_17  0.09902120  1.3616885 -0.8389882 -1.06493722  2.11316802  0.51066719
#> sample_18  0.44427911  0.3900637 -0.1194045  1.47496265 -1.29465826 -1.46761268
#> sample_19  1.36816180  0.8090419  1.0520439  1.57671017  1.15202991 -0.51774286
#> sample_20 -0.53069581  0.1306995  0.8770613  0.55789393  1.15001554 -0.28230468
#>               gene_68     gene_69    gene_70      gene_71    gene_72
#> sample_1   0.13167063  0.48862881 -1.6994506 -1.470736306  0.2841503
#> sample_2  -0.25692118 -1.05633610  0.1987772  0.650533552  0.3439133
#> sample_3  -0.70056001  0.53788544 -0.3163322 -0.839622754 -1.3549281
#> sample_4  -0.97007381 -0.22902736 -0.9748457  2.692372420  1.3923939
#> sample_5  -0.09620553  0.69450905 -0.4745912  1.763130612  2.0258461
#> sample_6   0.81959245  1.01340453  1.0536053 -0.071428639  0.9524446
#> sample_7  -0.63903369  0.39890294  1.3419735 -0.037607422  0.5436701
#> sample_8  -0.97164065  1.06858736  2.3162529 -1.682873392  0.1358754
#> sample_9   1.00675166 -0.04620091 -0.6523306 -0.977249153 -0.2599371
#> sample_10  0.29260865  0.33223639 -0.2319348 -0.815807168  0.2160748
#> sample_11 -0.42270349 -1.11699055 -1.3732054 -0.464627202 -0.7519824
#> sample_12  0.89257730  0.03875288 -0.0383727  0.811453346  0.0334869
#> sample_13 -0.19862421 -1.45337500  0.1984346 -1.391001690 -2.2442351
#> sample_14 -0.77721893 -0.95031824  1.2305163 -0.290321330 -1.2452496
#> sample_15  0.98668840  0.03235905 -0.4960436  1.673249059 -1.0512666
#> sample_16 -2.27919122  0.60007689 -0.3465782 -0.285153672 -0.6476522
#> sample_17  1.20026303  1.04546006  0.7204436  0.502968407  0.9558412
#> sample_18 -0.21130073  0.41961873  1.4333404 -0.737468113 -0.1250153
#> sample_19 -0.63501282 -0.40012391  0.5932415 -0.001094905 -1.8902278
#> sample_20 -1.74263112  0.40134331  0.6490598  1.087865196  1.1591175
#>               gene_73     gene_74     gene_75    gene_76     gene_77
#> sample_1   1.33732041  0.23669628  1.31829338  0.5239098  0.60674805
#> sample_2   1.47753231  0.07202570  2.12644453 -1.4761969  0.40788850
#> sample_3  -0.81756827 -0.63440000  0.81594943  0.3027957  1.80708662
#> sample_4   1.36007615 -0.36541588 -0.86893720 -0.5065567  1.21470730
#> sample_5   0.42761881 -0.56647935 -0.83383531  0.3982592 -1.47453793
#> sample_6  -0.38403752 -0.41775999 -0.47026817 -1.6901803 -0.94549766
#> sample_7   1.74021839 -0.32445594 -0.44751133  0.4160825 -1.29586537
#> sample_8   0.49843777  1.33346297 -0.02295457 -0.1915232 -0.44061489
#> sample_9  -1.55323598 -0.04525281  0.67735566  0.5361250  0.61687349
#> sample_10 -1.13886579  0.14010501 -0.66213391 -0.5343918 -1.41283088
#> sample_11 -0.40797454  0.17718257  0.99932634  0.1162693 -1.83506531
#> sample_12  0.66331887 -0.22009180 -0.01573655  2.0877135  1.49658665
#> sample_13 -0.23179244 -0.68655136 -0.48291528 -2.2435083 -0.38107857
#> sample_14 -0.92511062 -0.35175827 -0.04163083  0.7292974  0.29340303
#> sample_15  0.02801582  0.52689009  1.27078692 -0.5875924 -0.43047144
#> sample_16 -1.27221470 -0.17517318 -2.20131958  0.5798760  0.06279647
#> sample_17  0.49212806 -0.15594947 -0.43306218 -1.2234204 -0.29034337
#> sample_18  0.27982415 -0.44737203  0.04795768  1.0928525  0.50800968
#> sample_19  1.46147713 -0.39373425  0.58857701 -1.0594613  0.70208360
#> sample_20 -1.51050449  0.11420660 -0.16187819  0.5521627  0.34873345
#>               gene_78     gene_79     gene_80    gene_81     gene_82
#> sample_1  -0.10993567  0.17218172 -0.09032729  1.9243433  1.29839276
#> sample_2   1.39397780  0.36027830  0.65455025  1.0521554 -1.97955513
#> sample_3  -0.89402676 -0.04642821 -0.47117914 -0.5266926 -0.09513491
#> sample_4   0.50695868 -2.09497131  0.03407924  0.8527287  0.74322814
#> sample_5  -0.39544120 -0.13070247 -1.99949395 -0.9959309  0.42011400
#> sample_6  -0.34301196  0.35846241  0.04818886  1.1301723 -0.52763231
#> sample_7   0.68263309  0.49691333  1.43966066  1.2073586  0.23851469
#> sample_8  -1.94140598  1.41570672  0.59639966 -0.6529223 -0.15414467
#> sample_9  -0.66143654  1.33858671 -1.11781788  0.6847335 -0.61055634
#> sample_10  1.21720350  0.42553189 -0.12092861  0.6514307  0.49020556
#> sample_11 -0.29869568  0.31465272 -1.08246616  0.2217930 -0.04985130
#> sample_12 -0.30976402  1.58429093 -1.14727838  0.9379941 -1.17647338
#> sample_13  0.11604773  0.89249289  1.80852040  1.0796635  1.45205528
#> sample_14  3.58694548  0.75574301  0.40012730  0.8293457 -0.30513624
#> sample_15 -0.02296626  0.07487392 -2.08999562  1.0238972  0.62324013
#> sample_16  1.77512452  1.38369470  1.63096029 -0.8083913  0.09556545
#> sample_17  0.34023199  0.23455206  0.01182394  0.6047330  0.73750976
#> sample_18 -0.86991080 -0.70267648 -1.35940727  0.3456470  0.42180548
#> sample_19 -0.25439009 -0.38045108  0.72205180  1.3278428 -0.12549250
#> sample_20 -0.06267922 -0.48282757  1.99597980 -1.2515096  0.52848796
#>               gene_83     gene_84     gene_85     gene_86     gene_87
#> sample_1   0.74879127  0.55622433 -0.54825726  1.11053489 -2.61233433
#> sample_2   1.20838561 -0.16928008  0.29502975  1.26634059 -1.13534326
#> sample_3  -2.49536481  0.16688922  0.35049238  1.43370101  0.76590680
#> sample_4   0.55715361 -1.24858322 -0.20787431  0.42396946 -0.50669744
#> sample_5  -0.06286163 -0.08013185 -0.03228341 -0.71898093 -1.11656132
#> sample_6   0.47957533  1.41752930 -0.08009077 -0.39418700  0.52525764
#> sample_7  -0.29883788  1.38462105 -0.70006902  1.86093151  1.80392496
#> sample_8  -0.44364566 -0.51823378  0.20610706  1.63945367 -1.56473471
#> sample_9  -0.34930683  1.13396930  1.53375658  1.10666929  0.34406175
#> sample_10  0.70519246  0.80565067 -0.17999058  1.07286188 -0.08252346
#> sample_11  1.10753487 -0.99336062  1.92484347 -0.55676240  0.32947466
#> sample_12  1.40213301 -0.17717538 -0.65060426 -1.22936441  0.25132590
#> sample_13  2.55692359  1.07272807 -1.17891499  1.07541713  0.05385509
#> sample_14  0.71010332  0.43861382  0.35822370 -0.12423765 -0.69321609
#> sample_15 -1.36733001  0.04458952  0.36627380 -0.17846970  2.10167759
#> sample_16  0.91680819  0.47384354 -0.39524572  0.42939854  0.85093079
#> sample_17 -0.89810349  0.17182136  0.91323479 -1.10515345  0.39345014
#> sample_18  0.32671167 -0.96357511  0.47865798  0.78056492 -0.18542550
#> sample_19  1.13979470 -0.78440664 -0.47058964  2.61884348  1.78197043
#> sample_20 -1.24761627 -0.04165134 -1.05473729 -0.09817368  0.26143179
#>              gene_88       gene_89     gene_90    gene_91    gene_92
#> sample_1  -0.1556938  0.4338897899 -0.38195111  0.4241876  1.0631020
#> sample_2  -1.1310538  0.1099933842  0.85290541 -0.2343379  2.0866886
#> sample_3   1.1675207 -0.1369434286 -0.51490204  1.5197445 -0.3284917
#> sample_4  -0.6115233  2.4116594528 -0.16495814 -0.4404060  0.5219762
#> sample_5  -0.7802699 -1.7769585287 -0.42783487 -2.0310270  2.7507648
#> sample_6  -0.7959351  0.2450964484 -0.77931984  0.5949239  1.1088909
#> sample_7  -1.3560435 -0.3147510717 -1.01926518 -0.6122497 -0.2890687
#> sample_8   0.5115899 -1.5396613728  0.36279556  0.7707359 -1.2889862
#> sample_9  -2.0385797 -0.4934576343 -0.06079296  0.4382218 -1.2148912
#> sample_10  1.0725988 -0.0020797411 -0.85990532  0.7480741  1.3565154
#> sample_11  1.7582864  1.2739097903 -0.58388519 -0.3276924  0.1452413
#> sample_12 -1.5632154  0.8130799913 -0.11084868 -0.7611721  0.8295126
#> sample_13 -0.2343438  0.9507597343  0.07302193  0.6635280 -0.8161987
#> sample_14  0.5743465 -0.2171595152  3.03758116 -1.5916671 -0.6736892
#> sample_15 -0.2424097  0.0117172152 -2.77843369  0.2744914 -0.6227319
#> sample_16 -0.1703946 -0.0007914038  0.86064150  0.6403424  0.1068763
#> sample_17 -1.3698427  0.7394716153  0.63837094 -2.2803539 -2.0112247
#> sample_18 -0.3714158 -0.3759064151 -1.04977309  0.1355099 -1.0419342
#> sample_19  0.3112279  0.6046529221  0.80292536 -0.7421821 -1.0864863
#> sample_20  0.9101125  1.7078803398 -0.11685007  1.6786222  1.0147660
#>               gene_93     gene_94     gene_95     gene_96     gene_97
#> sample_1   1.04871262 -0.03810289  0.48614892  1.67288261 -0.35436116
#> sample_2  -0.11091937 -1.39284706 -1.14229077  1.70460874 -0.08007363
#> sample_3  -0.05367151 -0.56352463 -0.74390896 -0.10904165 -0.56082923
#> sample_4  -1.91832225 -1.98264996  0.52120016  0.77778320 -0.81211887
#> sample_5   1.51366972  0.03398894  0.74079278 -1.27080818 -0.16356423
#> sample_6  -0.94296903  0.70034399 -0.42467483 -1.14313760  0.23344022
#> sample_7   1.50698329  0.36772269 -0.02003494 -0.97992196 -1.40091233
#> sample_8  -0.71319437 -0.10238339 -0.64761175 -0.37325384  0.08334721
#> sample_9   0.49864688 -1.08286996  0.42216645 -0.22288872 -0.50032469
#> sample_10  0.40000160  0.63625661 -1.86603591 -0.58092724  1.09389613
#> sample_11  0.21410114  0.01155467  1.21969908 -1.03064364  0.76473497
#> sample_12 -1.05517196  0.22296796  2.44119504  2.00064170 -0.75480583
#> sample_13  0.29554426  1.34635766 -0.28001544 -0.06304363 -0.13283383
#> sample_14  0.72857280 -1.15156224 -1.15077521 -0.13207528 -0.58104636
#> sample_15 -1.02783172  0.72899011 -0.39246144  0.35784558 -0.75518986
#> sample_16 -1.46047776  0.45517138  1.27208468 -1.91518758  0.23558909
#> sample_17  2.06874056 -1.31505256 -1.10975040  0.05489672 -0.86258739
#> sample_18  1.37154346  0.21172302 -0.41999029 -0.51458174 -0.48118914
#> sample_19  1.58588835 -0.14070417 -0.97527663 -0.09184672  0.69744715
#> sample_20  0.14258127  0.02544607 -0.67845174 -0.37206424  1.21136061
#>               gene_98    gene_99    gene_100   gene_101    gene_102   gene_103
#> sample_1   0.94634789  1.3168264 -0.29664002 -0.3872136 -0.78543266 -1.0567369
#> sample_2  -0.43728124 -0.1192151  0.78646286 -0.5789452 -0.14542689  0.5264580
#> sample_3   0.18800155  0.7488509 -1.91653832  0.2360958  0.62895342  0.4179257
#> sample_4   0.91074832  0.9487540 -1.34804945  0.3541759  0.53026393 -0.3109749
#> sample_5  -0.61094549  1.2518842  0.25031947 -1.7055817 -0.85541313 -0.1449016
#> sample_6  -0.18923658 -1.6634113  1.91569077 -0.8168944  0.38365049 -0.4586323
#> sample_7   1.44501491 -0.4234816 -0.73374960 -0.7084848  1.47509246  0.8450042
#> sample_8   0.91721627 -0.2589533  0.67702573 -0.4201007  1.04720542 -1.5465763
#> sample_9  -1.10958579  0.9092090 -0.23396528  0.8424438  1.26409418 -0.7103473
#> sample_10 -0.53269110  0.6839841 -0.68426367  1.6259433 -0.63173445 -1.3537800
#> sample_11 -0.51498260  1.7409870  1.00584524 -1.1073529 -0.62788279 -1.4795019
#> sample_12 -1.30323896  0.2460262  0.54889371  0.4864143 -0.85724446 -0.2088896
#> sample_13  0.62936177 -0.6412315 -0.10401860 -1.3886688  0.43721421  0.3158621
#> sample_14  1.66135003  1.1679490  0.76988546 -0.1631158  1.27526535  0.1808880
#> sample_15  0.06668971  0.2573557 -0.09096306 -0.7305080 -0.39584125 -1.4158085
#> sample_16  1.05591431  0.4316772 -1.74594321  2.6345755 -0.03080357 -2.2561888
#> sample_17  0.93077549  0.5711704  1.23483193  0.4620031 -0.73420819  1.3233606
#> sample_18 -0.02289612 -0.2358174 -0.04291589 -0.5334722  0.24092366  0.2757880
#> sample_19  0.85019426 -0.2824700  1.05682051 -0.1645638 -0.50519732 -0.4024199
#> sample_20 -0.25107658 -0.5414573 -0.09333760 -0.5413840  0.07153290 -1.8226220
#>              gene_104    gene_105   gene_106   gene_107     gene_108
#> sample_1  -0.79554143 -1.75627543 -0.6905379 -0.5585420 -0.536663326
#> sample_2   1.73357811  1.44865722  1.5181931 -0.3840073  1.827125177
#> sample_3   1.97675848 -0.50628630 -1.1099689 -0.9487057  0.476843757
#> sample_4  -0.24415553 -0.29187819 -1.1280862 -1.1228816  2.053938640
#> sample_5  -0.32444696 -0.17256490 -1.2360629 -1.9023042 -0.094504024
#> sample_6  -0.71570398  0.42954854 -1.1698527  1.3220883  1.365964636
#> sample_7   1.29399443  0.29816114 -0.4056825 -0.1388076 -0.222592731
#> sample_8  -1.04600568 -2.27266976 -0.3166519 -1.4761906 -0.100387827
#> sample_9  -0.35382962 -1.08349099  0.9668578 -0.4805308 -1.041036179
#> sample_10  0.38712223 -0.96766752 -0.3587853 -0.5863974  1.612913478
#> sample_11  0.15434317 -2.29948441 -0.4387277 -0.6496806  0.424040947
#> sample_12 -0.02182835  0.37172886 -2.3006149 -0.6863915  0.823954712
#> sample_13  0.19461053 -0.45576213  0.8125350  0.2750426  0.006009411
#> sample_14  1.47436052 -1.51743472  0.3044004  0.1074674 -1.224792573
#> sample_15 -0.10893892  0.07429991  0.4501901  0.3873458 -0.258295014
#> sample_16  1.83682254  0.49853557  0.1562468  0.5565017  0.687106978
#> sample_17  0.45729477 -0.73648075  2.1436128 -0.3381594 -0.070970400
#> sample_18  0.98733788 -0.60717502 -0.2431552 -0.1837189  0.564549112
#> sample_19  2.29525136 -0.05804017  0.1223777 -0.2007777  0.460803569
#> sample_20  1.09916976  0.75587684 -0.3848796  1.0167902 -0.523622538
#>              gene_109    gene_110    gene_111    gene_112      gene_113
#> sample_1   0.22712713  0.97845492 -0.20888265 -1.39941046  0.2585372879
#> sample_2  -0.55149175 -0.86575354 -0.34383148  1.06287646  0.8130582040
#> sample_3  -0.79520156  0.23432692 -1.22245110 -2.45364735 -1.4892608139
#> sample_4  -0.90951843  0.45837916 -0.04661845 -0.68095460 -1.4888294023
#> sample_5   0.03255579  0.46129012  1.38140030 -0.41647627  0.6809426730
#> sample_6  -0.24972371 -0.42472135  1.09843934  0.67092304  0.0309546556
#> sample_7   1.74715026 -0.08170467  0.12414159  0.39223614  0.3784199701
#> sample_8  -0.74622261  0.20364588  0.49745036 -1.01428664  1.1457603469
#> sample_9   0.19962995  1.71290679  0.55273636 -0.86873581  0.0986371584
#> sample_10  0.50567134  0.02410609  0.29535965  1.27535036  0.2044771797
#> sample_11  0.04704973 -1.28504407  0.04553236 -1.44942970 -1.6337044027
#> sample_12  0.67156095 -0.13681109 -0.32485542  1.16536442 -0.9037414397
#> sample_13  2.01018641  0.31380882 -0.84616271 -0.13464105  1.4708322000
#> sample_14  0.44851998  0.50807095  0.35021264  0.75821367  0.2909287216
#> sample_15  1.52349060  0.55134344  0.32990177  0.17292270  0.4266415362
#> sample_16 -3.30418223  0.87832996  1.46117569 -0.10940668  1.3256063791
#> sample_17 -0.08821002  0.35509072 -1.20480846  1.45600050 -0.0004656092
#> sample_18 -0.64566331 -1.98419752 -0.93281079  1.86455975  0.3076683344
#> sample_19  0.64591565  0.28653862 -1.95530250 -0.07012252 -1.9934769567
#> sample_20  0.02745382  0.57984851  1.33528304  0.35862513  1.5526201263
#>              gene_114   gene_115    gene_116    gene_117    gene_118
#> sample_1  -0.44179945  0.5685999  2.12685046  0.42485844 -1.68428153
#> sample_2   1.80348336 -0.1050687  0.98245336 -1.71330262 -0.83201953
#> sample_3  -0.43214773 -0.9425540 -0.12145080  1.33644680 -0.86035618
#> sample_4  -0.39251301 -1.7496820 -0.03866763 -0.79715324 -0.91592054
#> sample_5  -0.41437304 -0.5183455 -0.68401973 -0.88564860  0.04923707
#> sample_6   2.36851196  2.5857881  1.21228095 -1.25119684  0.40026604
#> sample_7   0.16617567  1.1533874  0.01474830  0.02144084 -0.82635217
#> sample_8  -0.21441877  1.6748993  0.11636015  1.42656559 -0.23966733
#> sample_9  -1.83487472  1.4111949  0.37983102 -0.01567186 -1.57458146
#> sample_10  0.18674791  0.7097498  0.37584673  0.40541324  0.33098575
#> sample_11 -0.51728496 -0.9911514 -0.72848504  0.45195163  0.88718133
#> sample_12  0.98561211 -0.1263235 -1.44396717  0.03215408 -2.11771645
#> sample_13 -1.47512574  0.2044997 -0.34176842  1.84215765 -0.20590954
#> sample_14  0.02285959 -0.2081431 -0.26361162 -1.98413580 -0.35762022
#> sample_15 -0.81369958  0.6513551  0.91998180  0.39010179  0.95672410
#> sample_16  1.14068057 -0.9303642 -0.19462334  0.92400727 -0.28377136
#> sample_17 -0.11762366  0.1841482 -0.86120072  0.77931085 -0.45406417
#> sample_18 -1.87347681 -1.3815864  1.21428100  0.14148190  0.06310385
#> sample_19  0.12113268  0.4355959  0.13890432  0.98249750 -0.28639140
#> sample_20  1.56769961  0.7985797  2.60505344  0.71011685  0.15292829
#>              gene_119   gene_120     gene_121    gene_122    gene_123
#> sample_1   0.24940178  1.0728383  2.039369263  0.44945378  1.39181405
#> sample_2   1.10049188 -0.1738201  0.178812018 -0.69842945 -0.96044916
#> sample_3   0.66653782 -1.4215347  1.170056168 -1.40471454  1.10170810
#> sample_4   0.07326746  1.2381713  0.718371336  0.53946650 -1.06123399
#> sample_5   0.18556122 -0.6086578 -0.731102853  2.71514421 -1.33938704
#> sample_6   0.93470763 -0.4726698  1.583013221  0.59775422  0.46608459
#> sample_7   0.04739913 -0.2931074  1.207632181  0.03200138  0.18039755
#> sample_8  -1.10547392  0.3228977  0.021746800  0.31762482 -0.96970084
#> sample_9  -0.35254278  0.6218104  0.413433266 -0.09919527 -0.19602335
#> sample_10  1.59376051  0.5550758 -1.209478318 -0.22555795 -0.34238184
#> sample_11  1.26457340 -1.2914194  0.182510306 -0.08980967 -0.11262928
#> sample_12  1.66581693  0.5756711 -0.002235961 -0.72201499  0.44867236
#> sample_13  1.50223128  0.2421881  0.053455720 -0.12514631  0.24778724
#> sample_14 -0.45429735  0.2861577 -0.289179390  0.51190457 -1.10433455
#> sample_15 -0.16997356 -0.3799779  0.144207957 -0.71828409  0.20610865
#> sample_16  0.64381884  1.2049300 -0.986433477  1.36299940 -0.63713664
#> sample_17 -2.02860718  0.1374981 -0.653165249  0.72003510  0.80843643
#> sample_18  1.23546127 -1.0965462 -0.678783706 -0.55986724  0.21547636
#> sample_19  1.69415206  0.5213108 -0.471600217 -0.38675844 -0.03292149
#> sample_20 -0.10524807  0.4496792  0.499605216 -0.18600815  1.24476382
#>              gene_124    gene_125    gene_126    gene_127    gene_128
#> sample_1   0.42656655  0.10758399  0.02229473  0.60361101 -0.26265057
#> sample_2  -0.97542304 -0.33857650  1.15234707  0.40510118 -0.47092250
#> sample_3   0.69798626 -0.86434980 -1.09147035 -0.03705146  0.81005379
#> sample_4  -0.54073787 -0.71520471 -0.17892009  0.16497028 -0.72740817
#> sample_5  -0.64601525 -0.93245461 -0.76908693  0.37157978  0.35543278
#> sample_6  -0.74436754  0.95905526  0.15263708 -0.76936870  1.39308074
#> sample_7   0.07716058  0.55839534 -0.16685437 -0.22798062  0.24266606
#> sample_8   1.43446772 -0.98880485  0.39634960  0.52005742  0.71647258
#> sample_9   0.62116236 -0.04749709 -1.09567871  0.59783572 -0.81012801
#> sample_10 -1.73655950  0.16356090  0.29829351  0.17587003 -1.40560101
#> sample_11  0.16280134  0.55586101  0.85339468 -0.19489936 -0.04341191
#> sample_12  0.05173624 -1.25364945  0.55837496  0.29870240 -0.41552883
#> sample_13 -0.62661258  0.68287753  0.58960606 -0.81496732 -0.34579899
#> sample_14 -0.22247479 -1.45215149  0.39929877  1.42857119 -0.48214099
#> sample_15 -0.36733436  0.78844288 -0.31095280 -0.85914010  1.08527966
#> sample_16 -1.25270514 -0.57513773 -1.67630082  0.26281202 -1.42088329
#> sample_17  0.96245213  0.10313807  0.68636015  1.09519893  0.18189222
#> sample_18 -2.05543520 -0.52040863  0.25226391  0.15315642  0.49212442
#> sample_19 -1.58992520 -1.63163038 -0.61921693 -0.42856386  2.14362344
#> sample_20 -2.63185225 -2.77102642 -1.01858378  0.67406362  1.12914819
#>              gene_129   gene_130    gene_131   gene_132    gene_133    gene_134
#> sample_1  -0.52826408  0.1921494 -1.14619967  0.8461847  0.08171963 -1.30511701
#> sample_2  -0.13325102  1.2266824  0.33294400 -0.3470885 -0.09855069  0.03476606
#> sample_3  -0.49935541  0.9480316 -0.17424596 -1.1062360 -0.94598501  0.28908959
#> sample_4  -0.53783713 -0.5996649  1.18208775  0.1892129  0.24894911  1.04664341
#> sample_5  -0.98399849  0.2147296 -0.08008508 -1.4223695  1.10814896  1.07847764
#> sample_6   0.91866877  1.0160871  0.53463544 -0.9876286  1.18779227 -0.51754221
#> sample_7  -0.92848297  1.5154067 -0.81159882  1.3112474  0.81556680  0.12003267
#> sample_8  -0.06111581  2.2743766 -0.89763720  0.6180378  0.07756352  0.71350068
#> sample_9   0.81911755  1.1047006  1.41998840  0.5018139 -1.29236569  0.81758778
#> sample_10 -0.21525589 -0.5026803  1.68388170 -1.7250366 -0.25255476 -1.60486801
#> sample_11 -0.52943832 -0.5985106  0.14929768  1.2558209 -0.23436953  1.42234028
#> sample_12 -1.62537447  0.2996475 -0.14600795  0.3304704 -0.34435848  0.89176234
#> sample_13  0.05652905 -0.5667662 -0.04283746 -1.2815593  0.96758224  1.02904885
#> sample_14  0.99238818 -1.1637007  1.62078912 -0.1074482 -0.77320677 -0.73627880
#> sample_15 -0.78477932 -1.2209602 -1.05669143 -0.9968906 -0.67260509  0.66526837
#> sample_16  0.77384672 -0.6301914 -2.52322297  1.0456761  0.75134023  0.79816085
#> sample_17 -0.19687542 -0.8480614 -1.87744308 -2.5861413  0.10806723 -1.83834195
#> sample_18  0.53382238 -0.2071324  0.03511990 -1.1209760 -0.33196587 -1.27725513
#> sample_19  1.38105533 -0.9818231  1.31291728  0.3723740 -1.56624353 -0.82726234
#> sample_20 -0.66209099 -0.3008095  0.31127859 -0.4458649 -0.53930173 -0.56814019
#>             gene_135    gene_136     gene_137    gene_138    gene_139
#> sample_1  -0.9449121  0.45434159 -0.855202501 -0.28689522  0.89496163
#> sample_2   0.3861270  0.02083123  0.007586777  0.93084403 -0.68474994
#> sample_3   0.8769131 -1.14890394 -1.137612756 -1.43724674 -0.49414348
#> sample_4  -1.2893009  0.37511557 -0.556918391  0.30242663  0.22226647
#> sample_5  -0.4402503 -0.77816901 -1.818590012 -1.12408090  1.06052384
#> sample_6  -0.2595603 -0.32806467  0.073432395 -0.24786302 -1.37386226
#> sample_7   0.8817898 -1.79874312 -0.957051078 -0.47405861 -1.86046128
#> sample_8   0.5262098 -0.47055573  0.608828550  0.77324476 -0.81974820
#> sample_9  -0.7008723 -0.36089757 -0.682321746 -1.13663536 -0.56422337
#> sample_10  1.1533763 -1.26636306 -0.250127880 -0.53898858 -0.61115939
#> sample_11  0.2921275 -0.73688675 -0.129996552  2.20088565  1.61308129
#> sample_12 -0.1362943  0.28119119 -0.110812460 -0.03624743  0.02497722
#> sample_13 -2.1664253 -0.30334822  0.179268039  1.42739582 -0.61994660
#> sample_14  0.8157067  2.20303644 -0.671046628 -0.42158960 -0.77774912
#> sample_15  2.2360777 -0.60179817 -0.291617742 -0.84097486  2.03169952
#> sample_16 -1.5676418 -1.14747686  0.435586722  1.05320042  0.96350660
#> sample_17 -0.1230853  0.14748788 -1.430646410 -0.10598808  0.50318191
#> sample_18  0.5386513  1.34884128  0.601111502 -0.01271959  0.71613900
#> sample_19  1.0434322 -0.56181871  0.458990225  0.46117549  0.58820968
#> sample_20  0.9870993 -2.04078284 -0.106364577  1.72622018  0.41777402
#>              gene_140    gene_141    gene_142     gene_143    gene_144
#> sample_1   0.06730444 -0.16267634 -0.82731017  1.876505621  0.76644020
#> sample_2   0.33740151 -0.41213770  0.93426113  1.840316741 -0.70481966
#> sample_3   0.84080181  0.79153412 -0.16884895  0.612722104 -0.77115892
#> sample_4  -0.96216696  0.05203237  0.90004038 -0.394900880  0.95414600
#> sample_5  -1.47870016 -1.55156017  0.77750668  1.068440137 -0.18358770
#> sample_6  -0.04044582  0.42153824  0.20159751 -1.697191918  0.64228768
#> sample_7   0.25369007 -0.21440171 -2.37018145  0.003258078  0.66974557
#> sample_8  -0.12842274 -0.36502280 -0.07478942 -1.096987881  0.96671333
#> sample_9  -1.34905562 -0.65088011 -2.56959690  0.331580338  0.50872867
#> sample_10  0.80783735  1.35796756  1.00092845 -1.258705305 -1.39542914
#> sample_11 -0.26749958  0.12760317 -0.37089274 -0.452402281  1.19747825
#> sample_12  0.13105356  2.59552392  0.41928399 -0.281698421  0.54486311
#> sample_13 -0.13184245  0.26755175 -1.45677852  0.234340520 -0.95152805
#> sample_14  0.56154237 -2.22250706 -0.69541367 -0.383549957  2.05856698
#> sample_15  0.42937213  0.81101752 -0.17429995 -0.316371483 -0.49300189
#> sample_16  0.69393094 -0.23007095 -0.93555861 -0.902620378 -0.03086009
#> sample_17  2.51268045 -0.44138135 -2.17899913 -0.678148968  0.72884727
#> sample_18  0.40563442 -0.35485229 -0.83125608  0.225022902 -0.68841187
#> sample_19  1.36518764  0.23758497 -1.30193238  1.737977175  1.46415154
#> sample_20 -0.29617740  1.02350289 -0.16971703 -0.873829353  0.23936987
#>               gene_145     gene_146    gene_147    gene_148    gene_149
#> sample_1   0.979956696  1.321780992 -1.11971083  0.51459982 -1.50909984
#> sample_2   0.008510312  2.034189886 -1.34168607  1.15897918 -0.20320896
#> sample_3   0.888628993  0.013214477  0.22533951 -0.72991521 -1.22248707
#> sample_4  -0.588214348 -1.476584527 -1.37777577 -1.34567231 -0.73663796
#> sample_5   1.558242931 -0.213242384  0.93053526  0.41081180 -1.27984430
#> sample_6  -0.995239613  0.963813900 -1.65603723  1.07086109 -0.10902636
#> sample_7   0.226820843 -0.591868492 -0.40541449  1.41422466  0.24162583
#> sample_8   0.939926947 -1.600175495  0.20853659  1.12126035 -0.65199540
#> sample_9  -0.497105594 -0.944389799 -1.19445969  1.35163231 -0.61388379
#> sample_10  0.326775093 -0.566269784 -0.04009321  1.00742594 -1.37352086
#> sample_11  0.961339696  1.099244552  0.05353454 -0.07108256 -0.26521262
#> sample_12  0.868230689 -0.206675268  0.07494732 -2.25090133  1.50096116
#> sample_13  1.898439401 -1.042770546 -1.33374629  1.76472481  0.50606343
#> sample_14 -1.107988264 -0.955938774 -0.63576842  0.76675745  0.68695810
#> sample_15  0.190778474 -1.103744984 -0.10641331  1.45899271 -0.30747430
#> sample_16 -0.868678225  2.187787504  1.53853015 -1.88207267  0.91587500
#> sample_17 -1.243432737 -0.588271977  1.10853913 -0.50237999  0.34729869
#> sample_18 -0.648787614  0.471731346  0.17460625 -0.39327487  0.12324058
#> sample_19 -1.344497531 -0.007853537 -0.70936074  1.41991032  2.10075387
#> sample_20 -0.024588325  0.858574530  1.30347614 -0.38867187 -0.02542339
#>              gene_150   gene_151   gene_152   gene_153    gene_154    gene_155
#> sample_1   1.53274148  0.4291474  0.1221034 -1.1380124 -0.55801513  1.05253854
#> sample_2  -0.37802855  1.7361110 -0.8452478 -0.9615715  1.01749105 -1.49605374
#> sample_3   0.40680517 -0.7510122 -0.1621165  0.3520101 -0.28905830  0.10466223
#> sample_4  -0.47011150  1.3806093  1.6750109  1.1769066 -0.14889834 -0.17782336
#> sample_5  -0.78236663 -2.2760834 -0.1263959  1.4481467 -1.44275737  1.46718718
#> sample_6   1.89918639 -1.1370307 -0.2797198 -0.8941291  0.13670185 -0.74916542
#> sample_7  -1.43608748 -0.3145527 -0.4805428  0.8362542 -0.05234929  0.95195762
#> sample_8  -1.09013527 -0.7121821 -1.3626567 -0.5006904  1.43847286 -0.51163769
#> sample_9  -0.66670168 -1.2925475  0.8227224  3.0080927  1.11924176 -2.82179908
#> sample_10  0.33085823  1.1436235 -1.3817136 -0.8440696 -1.83658348  1.04417083
#> sample_11 -1.08747279  0.1129953 -0.3687616 -1.8138184 -0.72799437 -0.32334346
#> sample_12 -0.48276894  0.6052106  0.8006855  0.3183622  0.10347211 -0.65763660
#> sample_13 -0.65529222  0.6675088  1.3728761  0.5945820  0.80930744 -0.92935172
#> sample_14  1.72142669  0.8513093  0.4299083 -1.0552777 -0.04588097 -0.13188138
#> sample_15  0.75718141 -1.7108254  0.5953096 -2.0679667 -0.08573976  0.03228655
#> sample_16 -0.40174001 -1.2568740  1.1843969  1.0085725 -1.06615212 -1.08021400
#> sample_17  1.74814679  0.4628553  0.7678697  0.4510162 -0.35257722  0.36645449
#> sample_18 -2.00666765  1.2097835  0.1403724 -0.8758279  0.96236474  1.19026769
#> sample_19  0.05642966  0.8055451 -0.1927300 -0.1205781 -0.24118531 -0.25572956
#> sample_20  0.24474896  1.9977416 -0.2927706  1.0305376 -0.77745608  0.53671114
#>               gene_156    gene_157    gene_158    gene_159    gene_160
#> sample_1   0.677683644  0.03849955 -0.35638119  0.78284410  0.80441162
#> sample_2  -1.184818730  0.63023437  2.10125251 -0.61373681 -1.63463827
#> sample_3   0.720186531 -0.61104608 -1.10691407  0.53480333  0.73606797
#> sample_4   0.803121858 -0.41579535  1.21248959  1.24036003  0.68567588
#> sample_5  -0.743299901 -0.30422384  0.33765806 -0.60750209 -0.29556027
#> sample_6   0.518199077 -0.19233721  0.02880981  0.35859089 -0.02899503
#> sample_7   1.494512798 -0.34421473  0.64577541 -1.53450055  0.59967251
#> sample_8  -0.001967701  1.78313450  1.03138098 -0.58070469 -1.59308498
#> sample_9   1.617287527  0.51382026  0.50278931 -0.73529158 -1.10851818
#> sample_10  0.215210107  0.80034961  0.71493303 -0.31717121 -2.25204512
#> sample_11  0.118178061  0.52272118 -0.39471204 -0.73826236  1.31970010
#> sample_12  0.033874701 -0.64975656  0.91123965 -0.04727292 -1.17851501
#> sample_13 -0.968882573 -0.56348305  1.88848871 -0.11676961 -0.04977844
#> sample_14 -0.319463558  0.47360616  0.81251610  0.25661233 -2.14876584
#> sample_15  0.289686397  0.80893807  0.32626247 -1.70385748  0.52550459
#> sample_16 -1.526590371 -1.37040043 -1.29356943 -2.96102971  1.12559568
#> sample_17 -0.488124872  0.87339001  1.79878062  1.05079521  2.17523064
#> sample_18  0.191977818 -1.82760053 -0.84007682  1.62339399  0.16004145
#> sample_19 -0.208778684  1.63874899  0.71425048  0.02173027 -0.71086416
#> sample_20 -1.035791458 -1.18413156  1.49607176  0.69457501 -0.87664820
#>               gene_161   gene_162    gene_163    gene_164   gene_165
#> sample_1  -1.900060823  0.9357843 -0.30905150  0.26306668 -1.7905919
#> sample_2  -0.010441117 -0.6565061 -0.66953344 -0.47858903  1.3194563
#> sample_3  -1.222501574  1.0214153  0.46516516  0.79047270 -0.1302648
#> sample_4  -0.026798678  0.3095805  0.24986433 -1.35646087  0.5993798
#> sample_5  -0.134537140  0.8147844 -0.27292173  2.15948580  1.0917376
#> sample_6   1.147042072  0.3735889  0.32333921 -0.82981932  1.3944626
#> sample_7  -0.504358892 -0.4069096 -0.46093521  2.21490843  1.4869678
#> sample_8  -0.489042542 -0.7527001  0.66537880  0.73566389  0.7307993
#> sample_9   0.717057189  0.4058569 -1.49918152 -1.22357851  1.4253480
#> sample_10  1.505248197 -0.4191479 -0.20817999  1.02500862 -2.1093522
#> sample_11 -0.547717472  2.1165307  0.23888968 -0.51596937  1.1587522
#> sample_12  2.242660967  1.4674856  0.55206173  0.35962252  1.8375217
#> sample_13  0.412530895  0.3390062 -0.21946394 -0.27992198 -0.1844666
#> sample_14  0.690108551 -1.7724438  0.54629404  0.01894582 -0.7487022
#> sample_15 -0.803033850 -0.2376557  0.85534906 -0.46948704  0.1180128
#> sample_16  0.004027538  0.1626712 -1.48392237  1.16486032 -1.2724193
#> sample_17 -0.183562863 -0.6867930  0.02529218  0.77703122  1.3580461
#> sample_18  1.600151269  0.1142747 -1.36542455  0.43853873 -0.9615073
#> sample_19  0.067650247  1.8673130  0.73932627  0.96568744  0.4693349
#> sample_20 -1.339466676  1.6479129  1.37148122 -1.06974569  0.7165765
#>              gene_166    gene_167    gene_168    gene_169     gene_170
#> sample_1  -0.78825884 -1.13302167  0.36365257 -0.28588791  0.517669134
#> sample_2   0.63656276  0.51432778 -1.75137511  0.89359752  0.223038372
#> sample_3  -0.93028533 -0.36485100  0.15387249  0.41315482  2.480823360
#> sample_4   0.00864779  0.09071661 -0.65705741 -0.48178225  0.017757879
#> sample_5   0.74338485 -1.20785935  0.32781805 -0.53416511  1.283946719
#> sample_6  -0.19154358  0.27227702 -1.08165901 -2.32939936 -0.549625959
#> sample_7  -0.35509886  0.87620374 -0.21469665  2.02079836 -1.838661562
#> sample_8  -0.52872847 -1.21231512 -0.61989903  0.78089750  0.096229707
#> sample_9   0.53548399 -0.47912410  0.70875558 -0.01094071 -1.392609039
#> sample_10  0.58115598  0.42747604  0.30971218 -0.34868080  0.472684011
#> sample_11 -0.63435781  0.86271083 -1.68157303 -1.63679212  1.430290161
#> sample_12  0.88327330 -1.71320146  0.29372860  1.33080754  0.001025496
#> sample_13 -1.13104119  0.59906814 -0.34502446  0.32868363 -0.002001793
#> sample_14 -0.79432104  0.30078439  0.05466585  0.36422911 -1.165186698
#> sample_15  1.24744155 -0.68839730 -1.38356958 -0.04293242 -0.209234230
#> sample_16 -1.11377867 -1.30693704 -0.17420823 -0.68325152 -0.621568286
#> sample_17  0.31194542  0.99119768 -0.38189865 -0.88026152  0.023068321
#> sample_18  1.21634889 -0.78071197 -0.68229321 -2.24342637  0.180276393
#> sample_19  0.73292806  1.33379773  1.33018264  1.94267087  0.454756408
#> sample_20 -0.99528984 -0.70912717 -0.13950019 -0.83563356  0.471752612
#>              gene_171    gene_172    gene_173     gene_174    gene_175
#> sample_1  -0.10290867 -0.97406959  1.27067230  0.960864787  0.76872137
#> sample_2   0.58081659 -0.17782142  0.74096671 -0.997443079 -2.93897756
#> sample_3  -2.17995674  0.42087458 -0.35752832 -0.646861514 -0.05014180
#> sample_4  -0.85953576  1.35770498  1.21506118  1.453912917 -0.08591198
#> sample_5   0.02893134 -0.39567707 -0.69486833 -1.492080701  1.44425724
#> sample_6  -0.07257999  1.03228840  0.21513853 -0.494340125  1.51213828
#> sample_7   0.17293716 -0.76324504 -1.11849291  1.197977461  0.98119391
#> sample_8  -1.56135026  0.69837422  0.03819575  0.234660661  1.02132847
#> sample_9   0.62494754  0.68071956  2.25114000 -1.842120983 -0.08893203
#> sample_10  0.70274265 -1.54379750 -1.13941942  0.370802634  0.24929181
#> sample_11  1.53937650 -0.07721086  0.72223242  0.762012389 -1.10521674
#> sample_12  0.94401212 -0.16311016  0.02093633  0.551059233  0.75481473
#> sample_13 -1.64364047  0.83014458  1.31130078 -0.725708977 -0.38834507
#> sample_14  0.26055583 -2.41711628  1.14908502  1.206579247 -0.43198213
#> sample_15 -1.46699345  2.23577838 -0.62514496 -1.167913785  0.14952883
#> sample_16 -0.15516323 -1.08649358  0.55022201  1.394780678 -1.58831926
#> sample_17  0.70839680  1.47107117  1.42318511 -0.731757253 -1.22786232
#> sample_18  0.78150664 -0.95723134  0.09140705 -0.415741978 -0.66142355
#> sample_19 -0.43587827  1.64225074 -0.11939130  0.003403357 -0.28766248
#> sample_20 -2.69476851  0.03481254  0.36256041 -0.332326497  0.34361037
#>             gene_176    gene_177   gene_178    gene_179    gene_180    gene_181
#> sample_1   1.0359308 -0.47388707 -1.2753349 -0.30562067  2.21176949 -1.04166838
#> sample_2   0.7190157 -0.69800504 -1.8941258  0.07629925  0.87530850  0.45382739
#> sample_3   0.4169428 -0.63258754  1.1501467 -0.23547591 -1.64310739 -1.50338215
#> sample_4  -0.6175688 -0.21826025 -1.3260052 -2.36220890 -1.40996955  0.25439714
#> sample_5  -0.3470174 -0.04025917  1.2466321 -1.34630152 -0.57390128 -0.70595925
#> sample_6  -0.5794633  1.67478963 -1.0009803  1.22270284  1.07718817 -0.61194546
#> sample_7   1.1917492  0.63283357  0.5328259 -0.82012190 -0.15932568 -0.01753212
#> sample_8   1.4751236 -0.04839839 -0.5946723 -0.47400609 -0.32636128 -1.18566168
#> sample_9  -0.6541858 -0.37108970  0.7321427  0.15818293  1.00547316 -0.29736137
#> sample_10  1.2404153 -0.37159405  0.9088430  0.77207338  0.36664713  0.23406305
#> sample_11 -1.4611686  0.29556190  0.6585265  0.64514272  0.62365346  2.31584930
#> sample_12 -1.0179046 -0.32052555 -0.4572396 -2.16867569  0.06640965  1.51311497
#> sample_13 -1.0424084  0.73996554 -0.3792280  0.85504041  0.92972681 -0.51142031
#> sample_14  0.1068567  0.48619572 -1.5534583 -1.08314239 -0.51601203 -0.20777098
#> sample_15  0.8613199 -1.04620341  0.1722600 -0.30702075  0.90334561  0.98524869
#> sample_16  2.0675835 -1.69711305  0.8605076 -0.37964349  1.84763011  1.03765618
#> sample_17 -0.8465572  1.64147824 -2.5369827  1.51496682  1.34446529  0.34221800
#> sample_18  0.6839716  0.89238434 -0.7269076  1.01574403 -0.39559343  2.15951107
#> sample_19  1.0049148 -1.51968149  1.0805889  0.43537143 -1.38914741 -0.64430493
#> sample_20  0.2736567  0.29355519 -1.0016032 -1.11856814 -1.53570924 -1.30346291
#>             gene_182    gene_183    gene_184   gene_185    gene_186   gene_187
#> sample_1  -1.1465239 -1.67532730  1.52593866  0.5541855  1.99311026 -0.1541207
#> sample_2  -0.8507169  0.56620161  1.15221195 -0.7561974 -0.48925833 -1.1660523
#> sample_3  -2.0505848 -0.75319823 -0.13414196  1.0057828  2.16718680  2.3225565
#> sample_4   0.2958703  0.05678979 -0.10265486  1.9519230  0.87856596 -1.3066169
#> sample_5  -1.8574045 -0.24697048 -0.33556093 -0.2493769  0.45952256 -0.4600755
#> sample_6   0.5068670  0.46006837  1.48439186  0.8819632 -0.53670224  1.2855537
#> sample_7  -0.3906642 -0.40277511  1.27670696  0.8210758  0.41978515  1.7116612
#> sample_8  -0.9772881 -0.68267743 -0.03252769  1.4814811  0.02825460 -0.6880459
#> sample_9  -0.2354352 -0.26317085 -0.32046401  1.9306592 -2.18777451  0.7009740
#> sample_10 -0.8246375  0.79361376  0.81537558 -0.6404126  0.15466856 -1.3190621
#> sample_11 -0.3815989  0.03168816  0.77662540 -1.9830478 -0.00544671  0.7024117
#> sample_12  0.2425636  0.19609740 -0.65602378 -0.4783551  0.56887874 -2.1026268
#> sample_13  0.5756067 -1.17976074  0.87392273  0.7526550  0.63195295  0.4890517
#> sample_14  0.9072814  0.81142513 -0.99119325 -0.4543070 -0.31572854 -1.0063331
#> sample_15  1.6438285  0.81455972  0.82511316 -0.3457739  0.41114733 -0.6432144
#> sample_16 -1.4695748 -2.77694821 -0.07697979 -0.9544921  0.70867942  1.7770868
#> sample_17 -0.3246705 -0.95092126  0.12259632  2.2095975  1.30492804 -0.5255141
#> sample_18  2.2155816 -0.25571707  0.30229170 -0.6658051 -0.69606121  0.6833419
#> sample_19 -0.3177819 -2.61114258 -0.40407018  1.9639394 -0.90803824  0.2310028
#> sample_20 -0.4379984  1.94010248  0.33976088 -0.2036577 -1.22498518  1.7463406
#>               gene_188    gene_189    gene_190    gene_191    gene_192
#> sample_1   2.564408338  1.06199914  1.14269488  1.12383884 -0.39700149
#> sample_2  -0.479668950  0.11534822 -1.76804841 -1.40763892  0.70917846
#> sample_3  -1.020423391  0.04881444 -0.77188863 -0.78523507 -0.72660303
#> sample_4   0.090344272  0.90235804  0.54942132 -0.86983920 -0.03921465
#> sample_5   0.058932798 -0.74259108 -2.16357400 -0.23289649  0.87490683
#> sample_6   0.587848533 -1.30848203  0.31672632  1.19415830  0.91305715
#> sample_7  -2.215632715 -0.18487820  0.67116824 -0.79514024 -1.56625783
#> sample_8  -0.894731112 -0.53317059  0.58385837 -1.26285999  0.89319710
#> sample_9  -0.376301495  0.33518102 -0.29352566  0.01114218  1.19801734
#> sample_10 -0.559444239 -1.27868371 -0.16185463 -1.21269805  1.37134562
#> sample_11  1.223164016 -0.14139745 -0.49537901  0.84052263  0.56005014
#> sample_12 -0.003301496  0.41691801  0.47386760 -0.06292512 -1.63621935
#> sample_13  0.493466172 -2.02466874 -0.11534663  0.40296120 -1.32955321
#> sample_14 -1.016594660  2.02996478 -0.68763843 -1.58790685  1.01693810
#> sample_15  0.942059477  0.46959178 -0.66211224 -0.30947110  0.79457426
#> sample_16  0.866314308  0.15300582 -0.04638908 -1.67284741 -1.08989061
#> sample_17  1.151635923  0.82616690  1.15624483  0.41097269 -0.05604864
#> sample_18 -0.589274870 -0.07409355 -1.11227103 -0.59106225  0.85694461
#> sample_19  1.083031391 -1.02306279  1.97588492  0.50174849  0.93378365
#> sample_20  0.482781860  0.22318969 -0.94724382  0.03943565  0.59109249
#>             gene_193   gene_194    gene_195      gene_196   gene_197   gene_198
#> sample_1  -0.8232612 -0.5788846  1.76378938  0.1329921464  0.3764993  1.1387077
#> sample_2  -1.2408429 -0.3683273  0.46208009 -0.3228331007 -1.2872148 -1.0300402
#> sample_3   0.6818780 -0.2298433 -1.51060172 -0.5837276871 -2.0229185  0.4035047
#> sample_4  -0.5184517 -0.9118496  0.15031364  0.4403554485  1.3197821  0.2465611
#> sample_5  -0.9734940 -0.5127469 -0.92348799 -1.4944257251 -0.1659304  1.5822383
#> sample_6  -0.7867530 -0.4109297  0.47637368  0.1859158675 -1.3247163  1.1723711
#> sample_7   1.2137325  1.5038101 -1.16942502  0.6133771675  1.4839313 -0.4437737
#> sample_8  -0.8971835  0.5546127 -1.16400329  0.0186566700  0.3288212 -0.2949463
#> sample_9  -0.4677335  0.9163829 -0.70606033  0.7869355376  0.3998839 -0.6387053
#> sample_10  0.0826277 -1.2658538  1.17427579  0.6959916749  0.8000704 -1.0021969
#> sample_11  1.1370459  0.4738013 -0.15044036  2.1389952349  0.2179965 -1.8959692
#> sample_12  1.1682297 -0.4086862 -0.09411706  0.4675893086 -0.8281954  0.3968132
#> sample_13  0.8500323  1.1056819  0.40414191 -0.1231415112  0.4488477  2.0681537
#> sample_14 -0.7231022 -1.4534850 -2.14081548  0.1348544268  0.6619978  0.4946132
#> sample_15 -0.9148510 -0.4655203  0.81966936  1.5210357381  0.2653548  0.6190669
#> sample_16 -0.0761757 -1.3058317 -0.06238456  0.3423715685 -0.5489306  0.9150613
#> sample_17  0.7801771 -1.9231778 -0.27364949  0.6037177315 -1.3173483  0.9555886
#> sample_18  0.5088934  0.3971039  0.38675725  0.3701361846  1.0367231  2.3587651
#> sample_19 -0.4303948  1.3189214  0.78666256  0.3909081962  0.5550166  0.4958615
#> sample_20  0.9021147  0.3586921  0.61721477 -0.0003015099  1.1160198 -0.1324563
#>              gene_199    gene_200   gene_201    gene_202    gene_203
#> sample_1   1.24126308  0.61209094 -0.4293801  1.36046133 -0.07085743
#> sample_2   1.51408932  0.34690359  1.7794415  0.38663092 -0.91869524
#> sample_3   0.55001555  0.02835712  0.8931650 -0.37655550  0.60588481
#> sample_4   0.94182660 -0.34215133 -0.2761468  0.38365678  1.44691022
#> sample_5   1.01460227 -1.14647834 -0.9098491  3.10918268 -1.06955277
#> sample_6   0.23149277  0.48307190 -0.5353196  1.37813582 -1.30267167
#> sample_7   0.26858974 -1.22821683  0.4785288  1.66985957 -0.03645555
#> sample_8   0.64159990  0.92667781  1.7721240  1.66209268  0.02792891
#> sample_9  -0.34312141 -1.11827842  0.5783768  0.11318695  0.44020633
#> sample_10 -0.67711567  0.72096360  0.9601681 -0.14566567  1.50525554
#> sample_11 -0.14273839  1.46242573  1.0746571  0.65505667 -0.12313366
#> sample_12  0.24447551  0.62743759 -0.8052065 -1.93205307  0.71708201
#> sample_13 -1.24953684 -0.21953118  1.0320027 -1.58287658  0.08496778
#> sample_14 -1.52664365 -0.11021600  2.4687413 -0.56354343 -1.44585342
#> sample_15  0.47108084  0.46314421 -0.1601614 -0.03568547 -0.57468482
#> sample_16 -0.08760390 -0.02557947 -1.2543574  1.88012482 -0.14094937
#> sample_17  0.01285354  0.29143609 -2.0168056 -1.59648840  0.79051330
#> sample_18 -0.91360208  1.27559942 -1.4390901  0.03814221 -0.50357219
#> sample_19 -1.58883685 -0.32126448 -1.5520529  0.96151600 -1.08631527
#> sample_20  0.88813439 -0.05504630 -1.1447172  0.03108665 -1.52231049
#>               gene_204    gene_205    gene_206     gene_207    gene_208
#> sample_1  -0.272153684 -2.44668003  0.06548664 -1.098508902 -0.63317818
#> sample_2  -1.584336488 -0.08405889 -2.08507089  0.003567992 -0.35577082
#> sample_3  -0.004874726 -0.52079637 -0.63901860 -0.635894137  0.10658698
#> sample_4   1.733900291  0.45642938  0.70750349  2.063789224  0.02391059
#> sample_5  -0.700109518 -0.19844447  0.74362012 -0.050159767  1.31314355
#> sample_6   0.634857535  0.99965516 -0.33774895 -0.086033607 -1.71881758
#> sample_7  -0.440936271  0.73440889 -0.57530946  0.074897554  0.05930184
#> sample_8   1.615495109 -1.34752241  0.19362683  0.421505299 -0.50013320
#> sample_9  -2.002320938  1.04163384 -1.01374892 -0.504802858  0.08995304
#> sample_10  0.678180406 -0.26555220 -0.45813254  1.738431533 -0.01310595
#> sample_11 -0.929721805  1.51655653 -0.07679296 -0.369791935  0.60623267
#> sample_12  1.792486559  1.12319487  1.60994768  1.732799496  1.27570372
#> sample_13  1.210794619 -0.02346257  0.08469392 -0.325065508  0.50592356
#> sample_14 -0.476555776  1.01460047 -0.11802003 -0.354321844  0.28725584
#> sample_15  0.845350017 -0.58176612 -0.50235711  1.088076265 -0.39295302
#> sample_16 -0.106691137  0.72455509  0.42881808 -1.580215751  0.77475581
#> sample_17 -0.055953771  2.78465654  0.39541170  2.697962419  1.05661013
#> sample_18 -1.713177445  0.75245163 -0.88340211  0.136518779  0.42628188
#> sample_19 -1.716257245 -0.35522618  0.97927600 -1.174070697 -0.39646086
#> sample_20 -0.530314430  0.01026276 -1.58592694  1.150015160 -0.14541101
#>              gene_209     gene_210    gene_211    gene_212    gene_213
#> sample_1  -2.06365445  2.648932029 -1.15339839 -0.34063788  0.78636258
#> sample_2   1.14635975 -0.221188446  1.01817902 -0.26371930  1.65854230
#> sample_3   1.17691425  0.447391153  2.27295477  0.13605821 -1.99903913
#> sample_4   0.24594946  0.272059145 -0.99245858 -0.02757795  2.22284516
#> sample_5   0.08601352 -0.629851372  0.65507033  0.01939355  0.69626996
#> sample_6  -0.92912157  0.813676046  0.52641355  1.01195739  0.83137981
#> sample_7   0.84826470  2.575396587  0.09425996 -0.51994953  0.77442862
#> sample_8  -1.59442601  1.417076086  1.05056411 -0.58443191 -0.52671487
#> sample_9  -1.29200091 -1.730530080  1.13242478  0.95539852 -0.71400828
#> sample_10 -0.79435335  0.255333393 -0.87877765 -0.50238401  0.91823511
#> sample_11  1.52673800 -0.081510851  1.42835885  1.01357184 -0.67657783
#> sample_12  0.42400799 -0.137778131 -0.59793732 -0.72207327  0.07276248
#> sample_13  0.41527205 -1.177413897  0.03344533 -0.67987338  0.97781403
#> sample_14  0.01801262 -0.898423976  1.44473649 -0.53779915 -0.48236000
#> sample_15 -0.66046112 -0.149025127 -0.87548530  1.69900157  0.06819026
#> sample_16 -1.16429212  0.008854303 -0.45507800 -1.00269005  0.42806957
#> sample_17  1.78186931  1.318688039 -0.72408315 -0.26329117 -0.34859075
#> sample_18 -0.92513975 -0.969095736 -0.22658278 -0.97822396 -0.53335413
#> sample_19  0.02895934 -1.470506429  0.96517223 -0.78144169  1.25731934
#> sample_20  1.61724620  0.135390016  0.44055001  0.63818265 -1.08707192
#>             gene_214    gene_215   gene_216    gene_217    gene_218    gene_219
#> sample_1  -1.2705131  0.54214155  0.0751059  0.55851442  0.41540640 -1.45229977
#> sample_2  -0.7740868 -0.92393788 -0.2755334 -0.59339969 -0.12228589  1.17978425
#> sample_3  -0.4205009 -0.37840740  1.2207748 -1.54103029 -0.31031012 -0.02010818
#> sample_4   0.1555039 -0.86911632 -1.1744894 -1.75967731  0.05836159  1.16451986
#> sample_5   2.0088699 -0.05697828  0.2404155 -0.02189017 -0.83080816  1.40247432
#> sample_6   0.4151341 -0.66125706  0.5488113 -0.53936780 -0.17131843 -0.76673461
#> sample_7   1.2282893  1.88060688 -0.1252417 -0.75909477 -0.50930360 -0.15603967
#> sample_8  -0.1222407 -0.58632828 -0.2478669  0.80125715  2.52510877  0.27003304
#> sample_9  -0.1303939  0.95080488  0.4707942  0.33483813 -1.54942326 -0.62115042
#> sample_10 -0.4155561 -0.49745413  0.1229840 -0.99409384  0.48593786 -0.55104176
#> sample_11 -0.2365657  0.50559912 -2.5277529 -0.70066867  0.09160758  0.85217358
#> sample_12  1.4733625 -0.31620608 -1.4147214 -1.98617904  0.70573403 -0.79042763
#> sample_13  1.7724774  0.27793329 -0.4810193 -1.79106060  0.53066370 -1.12476618
#> sample_14 -0.7356196 -0.01523526 -0.2850608 -0.77089599 -1.91152294  0.17789966
#> sample_15  0.5331876 -0.08094899  2.4467814  0.38389903 -1.05217158 -1.72223383
#> sample_16  0.2025623  0.18158328  0.5656939 -0.27765698 -1.36424848  1.29920725
#> sample_17 -0.2132519  0.74866647 -3.0045498 -0.20571019 -0.14351672  1.31095720
#> sample_18  0.8663929 -0.49338094 -1.2286158  1.28456315  1.21178017  0.01786708
#> sample_19 -2.0462473  1.81907819 -1.3673821  0.37197567  0.75249610 -0.84410270
#> sample_20  0.3246503 -2.02073388 -1.5803093 -0.20044943 -1.13113806 -0.78680531
#>              gene_220    gene_221    gene_222     gene_223   gene_224
#> sample_1   0.94120612 -0.33893587 -0.07557425  0.040204392  0.1243011
#> sample_2   0.64103737 -0.62958851 -0.80773497 -0.860489929 -2.1692387
#> sample_3  -2.39020034  0.88986536 -1.48281332  0.445750348  1.3697759
#> sample_4   0.33762789 -1.05451872  0.66076911 -0.823409004  0.4370337
#> sample_5  -0.72386911  1.33058037 -0.81133302  1.795036105  0.6866263
#> sample_6  -0.60657485  1.64731282  0.84106935  0.338175097 -0.4048831
#> sample_7   0.13258244 -0.97408402 -1.25094966 -0.046336042  1.1373878
#> sample_8  -0.88635703 -0.76952385  0.45405702 -0.706657247 -0.9493955
#> sample_9  -1.61561823  0.85346537  1.88881916 -0.867441159  0.7144205
#> sample_10  0.16660082  0.09556492  0.93736174 -0.778592244 -0.3460150
#> sample_11  1.12390932  0.82786930 -1.36811281  0.189759677  1.9607559
#> sample_12  0.75848016  2.07837562  1.91913490  0.075529822  0.2677515
#> sample_13  0.04022615 -1.18796740  2.24883111  1.553161749  0.3230219
#> sample_14  0.19632069  0.05004416 -1.04527444 -0.136682386  1.2275006
#> sample_15 -0.63081925 -0.95359598 -0.07998247  1.062695902  1.3510568
#> sample_16 -1.99284656 -0.10371609  0.29976626 -0.403000409  0.3384910
#> sample_17  0.76457326  0.56446857 -0.17532139 -0.002574686  0.5887499
#> sample_18  1.70024778  1.34411535  0.24724950 -0.095850995 -0.1058948
#> sample_19 -1.47470376 -0.12728651 -0.11308334  1.806296611 -0.9163136
#> sample_20  1.76282435 -0.31614936  0.66981383  1.855952275 -0.4366507
#>              gene_225    gene_226    gene_227   gene_228   gene_229    gene_230
#> sample_1  -0.99843255  1.23339006  0.34042449 -0.4727025  0.7087531 -1.52895871
#> sample_2  -1.37583652 -0.49313247 -0.58165203 -0.1672293  0.4859931 -1.33339580
#> sample_3  -0.02011003 -0.10921759  0.26466174  0.3038483 -0.1833885  0.55964967
#> sample_4   0.37238811 -1.64674913 -1.92355227  0.3808330  1.3757053  0.82584873
#> sample_5   0.08937800  0.32454774  0.07131812  0.2330484  1.9863766 -0.95167079
#> sample_6   0.90000904  1.19066666 -0.04753908  0.7869254  1.1666841 -0.27182387
#> sample_7   1.26444989 -0.54874208  0.68239143 -0.9297734 -0.9751487 -0.02711708
#> sample_8  -1.06640060 -0.88645119  0.66859230 -2.0675643  1.6941464 -0.18977036
#> sample_9   0.61442702  0.30509874 -0.92599980  1.3595344  0.2036983  1.28854351
#> sample_10  0.14592795 -0.67937828 -0.61369825  2.2029351 -0.3287725  1.75177685
#> sample_11 -0.80601772  0.24735027  0.50782823 -0.4958018 -0.9021024  1.01253254
#> sample_12  0.43629074  1.20974878 -1.25305556  1.7650286 -0.1593220  0.89887422
#> sample_13  0.02275970 -0.24942787 -2.17231912 -1.3396591 -0.9804858 -1.79278068
#> sample_14 -0.19386519 -1.99307110 -0.42990567 -0.6519163 -1.3227553 -0.61100236
#> sample_15  0.23329022  0.33389879 -0.76477026  0.7693845 -0.2150130  0.38338059
#> sample_16 -1.47842704 -0.04651493  0.03168819  0.2815326  0.8031953 -0.20885835
#> sample_17  0.17531716  1.39692297  0.82541665  0.5547305  0.5453780 -0.53638450
#> sample_18 -1.26115471 -1.76021040  1.79143081 -0.8010346 -0.5579332  0.75611749
#> sample_19  0.32603605  1.72940636  0.61863103 -0.2435104  0.3041536 -0.15611053
#> sample_20  1.68348793 -0.22829121  0.83479832 -0.6273759 -0.1228997  0.63543146
#>              gene_231   gene_232    gene_233    gene_234    gene_235   gene_236
#> sample_1   0.23742535 -1.3128142  0.74702859 -1.56251843  0.07105336 -0.6395348
#> sample_2  -0.26196562  0.6523863  0.74885497  0.89656029  1.48930042 -0.6594035
#> sample_3  -0.18655384 -0.8122754 -1.64058167  0.50792248  1.75433696  0.5924002
#> sample_4  -0.41611500  0.9821496  0.24218073 -0.93792685  1.50585850 -1.0658512
#> sample_5  -0.55864232  0.2558145 -0.19807617  0.42878914  0.07077011 -1.5366538
#> sample_6  -0.31370428 -0.2863002 -0.80344026 -0.09455546 -0.07404651  0.7144907
#> sample_7   0.44667189 -0.3291122  0.11304908  1.05122939  0.32697740  0.7870374
#> sample_8   0.42216699 -0.6631157 -0.66276546  0.11329221  0.94295108 -1.2158733
#> sample_9  -0.21297183  0.4875498 -1.06770917 -1.18048867  2.15917576 -0.4178126
#> sample_10 -0.97165174 -1.6895469 -1.48138618  2.42689478 -0.22846002  1.1132835
#> sample_11  1.63654057 -0.8255205 -1.30128401 -0.48404261 -0.19156194 -1.2039913
#> sample_12 -0.70499533  1.1268966 -1.97432221 -1.24477283  1.03125039  0.5790970
#> sample_13  0.52281281 -1.5913285  0.80626313 -0.68381307  0.33438806  0.9430064
#> sample_14 -0.43348477  0.2211316  0.41463530  1.00351963 -2.62604224 -0.8735349
#> sample_15 -0.54249536 -2.0945782  0.37805006 -0.70593423 -0.58710453  0.1000864
#> sample_16 -0.33672818 -0.4563098  1.02426031  1.45739515 -0.22493059  0.2900685
#> sample_17 -1.83926751 -0.7123422 -0.09456646  0.24301597  1.02044611  0.9232620
#> sample_18 -0.06565428  1.4038251  0.80612311 -0.12533444 -0.56442254  0.9407780
#> sample_19  0.66641160 -2.1430249 -0.78568405  0.85631614 -0.35472132  0.1861089
#> sample_20  1.09852053 -0.2414560 -2.05220527 -0.83857490 -0.86128523  0.1587061
#>              gene_237   gene_238    gene_239   gene_240    gene_241    gene_242
#> sample_1  -0.84519574  0.6752447  1.15337579 -1.6865047 -0.90281495  1.31763370
#> sample_2   0.53728318  0.7468031  1.89631708 -2.0600707  0.06454387 -0.26514740
#> sample_3   1.01671329  0.1216206 -1.07806726 -1.1435657 -0.52964368 -0.68127316
#> sample_4   0.16227053  0.2604704 -1.48820199  1.4151839  0.56250751  0.64205574
#> sample_5   0.45398437  0.8743986 -1.29773757 -1.0789652 -1.13484994  0.02261431
#> sample_6   0.12471837  1.2965943 -1.11449293 -0.8420588 -1.50429421 -0.28402646
#> sample_7   0.44155962 -1.0193045 -0.15869833 -1.6377013  2.83926623  0.96181916
#> sample_8  -0.04726274 -0.1920450  0.63214857 -0.1519050  0.01520037  0.88871818
#> sample_9   0.08765496 -0.5437091 -0.11986702  1.8006249 -0.79424735 -0.36036056
#> sample_10 -0.43706385  1.2648846  1.43659773 -0.9186643 -1.91460251  0.11496953
#> sample_11 -1.55456583 -0.1492897 -0.98824895 -1.3005309  0.76400192 -0.76422002
#> sample_12 -1.03789001  1.5616223  0.10195962  2.3242383  2.32585155 -1.29314996
#> sample_13 -0.89838767  0.7673359  0.09233868 -0.3516960  0.11537300 -0.14326135
#> sample_14 -0.77371083  0.5930586  0.45356334 -0.4896267 -0.66608550 -1.08965423
#> sample_15  1.20206636  0.6598440 -0.62674536 -0.5297761  0.87650319 -0.05013821
#> sample_16  0.25927654  0.0098923 -0.18467393  1.6542466  0.43685436  0.84731611
#> sample_17  0.26317994 -0.6875862  0.22086118 -0.5541038  0.55184639 -0.16183299
#> sample_18  1.26980895  1.2650385  0.69953040 -0.4789323 -1.31420274 -0.90364582
#> sample_19  0.38589772  0.6055049  0.52212061  1.6078319  1.52866477  0.28576087
#> sample_20  0.14151503  0.5491975 -1.25469101  0.6528780 -0.17080138 -1.71282287
#>              gene_243     gene_244    gene_245    gene_246    gene_247
#> sample_1   1.10018974  1.203767839 -1.43127078  1.38291086  0.00312594
#> sample_2  -0.44734453 -1.410700927 -0.50641888 -0.26976184 -1.08515492
#> sample_3  -0.20244756  1.684495721 -1.03377324 -0.15597667 -0.04640064
#> sample_4  -0.89053264 -0.116537517 -0.94197475  1.11582792  0.47013513
#> sample_5  -0.02146122 -0.278772443 -0.02420641  0.82502030 -0.75018278
#> sample_6   0.04286904 -0.008866413 -2.94908378  0.02035825 -0.09844698
#> sample_7   0.50843200  0.259523192 -0.77340413 -1.80552753  0.17838323
#> sample_8   0.01033495  0.344932320 -0.91317842 -0.92439810 -0.37207719
#> sample_9   0.63146065 -1.663279352 -0.48800525 -0.02075222  0.93387104
#> sample_10  1.51034812 -0.009052613 -0.13585674 -0.33625067  0.35779653
#> sample_11  1.05984222  0.574400444  1.45435482  1.92660650  0.37769313
#> sample_12 -0.04501885  0.195694234  0.48062339  2.01734246  1.19560865
#> sample_13 -2.41982035 -1.163794035  0.10342665 -0.12614333 -0.14174341
#> sample_14 -1.04090695  0.501606680  0.04135376 -0.05308168 -1.52739908
#> sample_15  2.28039035  1.379810564 -0.57363603 -1.41683743 -1.24490746
#> sample_16  0.99628230  1.067452442 -0.05334258  0.99292623 -0.49935268
#> sample_17  1.35140353 -0.005333142 -2.40513344  0.98980936 -1.23303168
#> sample_18 -0.68267777  0.374599658  0.80978442 -1.02731189  0.27120472
#> sample_19  0.96647886  0.041676859 -0.18656805 -1.35109974 -0.95322589
#> sample_20 -0.09151897 -0.939603575  0.83190259  0.35367663  0.81208047
#>              gene_248    gene_249    gene_250
#> sample_1  -0.07788682  0.44142823  0.12892290
#> sample_2   0.36215913 -0.33567214  1.36380450
#> sample_3  -0.95362873  0.41626080  0.11402961
#> sample_4   0.86061271 -0.07039665 -0.61318021
#> sample_5   0.53621047 -1.57271748 -0.98642742
#> sample_6   0.58910910 -0.42575163  0.63465899
#> sample_7  -0.52577731  0.40018632 -0.12258759
#> sample_8  -0.29779785  1.57449189 -1.98066169
#> sample_9  -0.23267088 -1.01963006 -1.68032832
#> sample_10  0.34049858  3.09723070  0.67735274
#> sample_11  0.45781732 -0.31447817 -0.19633722
#> sample_12  0.65657552  1.02629785  0.52019266
#> sample_13  0.91043704  1.47761791  1.64624260
#> sample_14 -0.16356852 -2.13509492 -0.13683359
#> sample_15  0.90008248  1.98943026 -2.78697529
#> sample_16 -1.11639333 -0.97451676  2.78740354
#> sample_17  0.02741056 -0.39100523  2.40181018
#> sample_18  0.37216339 -1.47380351 -1.42279915
#> sample_19 -1.28260715  1.34873878  0.08748952
#> sample_20 -0.05053601  1.87464215  1.51944240